The chapter examines the philosophical underpinnings of Georg Simmel’s sociology, arguing that the various fragments of his thinking of social reality cannot be properly understood if they are disconnected from his philosophical concerns and the whole of his work. The emphasis Simmel’s sociology places on process resonates with his life-philosophy generally, and with contemporary problems of modern existence more particularly. While also situating Simmel’s ideas in their cultural and societal context, above all in relation to the revolution in modes of thinking and everyday perception connected to the mechanized culture of modernity, the primary goal of the chapter is to explore how his work might help us understand our present condition. Here, especially Simmel’s perspectives on the entanglement of humans with the broader, more-than-human world of natural beings, inorganic matter, and technological networks are foregrounded.