The growing emphasis on sustainability in the design industry has brought renewed attention to the potential of biodesign and biotextiles, particularly through the innovative use of bacterial cellulose (BC). BC is a biodegradable, versatile material produced by certain bacterial species. This study explores the potential and limitations of using BC in textile production, focusing particularly on its aesthetic qualities and how it performs in terms of comfort. The paper provides an overview of bacterial cellulose, emphasising its unique properties, biodesign strategies, fabrication methods and emerging applications. Using a Research through Design (RtD) methodology, the study includes experimental work on producing BC textiles. The study also investigates the application of natural dyes and laser-cutting techniques to enhance the material's visual and tactile appeal. The results suggest that BC holds significant potential for developing biotextiles, offering a balance of durability and aesthetic value. However, ensuring comfort remains challenging, highlighting the need for further interdisciplinary research and development. Ultimately, this study encourages designers to reconsider textile production through the lens of biodesign. Incorporating sustainable resources and living systems into the design process establishes the foundation for future advancements in regenerative and responsible textile practices.