Mandibular and maxillary bone regeneration is a significant challenge in orthodontics and maxillofacial surgery, particularly in patients with bone atrophy or advanced periodontal diseases. This study presents an innovative approach that integrates advanced imaging and manufacturing technologies to design and fabricate customized scaffolds based on data obtained through Cone Beam Computed Tomography (CBCT). The objective is to create biomimetic bone scaffolds suitable for infusion with autologous stem cells, promoting functional bone regeneration. The workflow comprises three key stages. CBCT images are processed to reconstruct detailed three-dimensional models of the mandibular or maxillary structure. Then, using generative optimization algorithms and surface subroutines in commercial CAD software, scaffolds are designed to replicate the mechanical, geometric, and biological properties of natural bone. The scaffolds are fabricated using 3D printing techniques with biocompatible and biodegradable materials. 3D printing enables high precision in creating porous structures optimized for vascularization, cellular integration, and mechanical support. This multidisciplinary approach, combining medical imaging, CAD/CAM design, and additive manufacturing, offers an advanced solution to address the challenges of bone regeneration in orthodontics. Preliminary results suggest that infusing scaffolds with stem cells could significantly accelerate bone regeneration and improve integration with surrounding tissues. Future studies will focus on preclinical validation of scaffolds.