Rift Valley Fever (RVF) remains a significant emerging zoonotic disease in many tropical regions, particularly affecting sub-Saharan Africa and the Arabian Peninsula. Driven by complex interactions among environmental, climatic, and socio-economic factors, RVF outbreaks have extensive public health, veterinary, and economic consequences. This chapter explores sustainable strategies for RVF surveillance and control within a One Health framework, emphasizing the integration of ecological management, community engagement, and technological innovations. The analysis focuses on the role of climate-sensitive drivers—such as rainfall variability, flooding, and ecosystem disruption—in shaping RVF transmission patterns, alongside the critical importance of early warning systems that combine meteorological data, satellite imagery, and participatory community surveillance. Sustainable vector control approaches, including habitat modification, biological control, and environmentally friendly larvicides, are considered alternatives to chemical-dependent methods. The chapter further examines livestock vaccination programs and adaptive livestock management as dual strategies to protect both animal and human health. Special attention is given to community-based risk communication, culturally sensitive engagement, and empowering local populations in disease prevention and response. Furthermore, policy integration, cross-sectoral coordination, and sustainable financing models are proposed to strengthen health systems’ capacity for long-term resilience against RVF and other emerging zoonoses. The chapter concludes by positioning RVF management as a model for sustainable tropical disease control, linking local practices to global health security goals.