ASEAN countries’ maritime transport and supply chain networks are critical to global trade and tourism, yet they face increasing challenges from climate change, geopolitical shifts, and pandemic-induced disruptions. This chapter focuses on rebuilding resilience in ASEAN’s maritime systems by examining key ports such as Singapore, Port Klang, and Ho Chi Minh City, which play diverse roles within the region’s interconnected network. Using a case study on the ASEAN cruise port network, the chapter introduces a vulnerability assessment framework that leverages social network analysis (SNA) and centrality measures, augmented with a COVID−19 Performance Index (CPI), to evaluate port-level and network-level impacts of local disruptions. Comparative analyses of pre-and post-pandemic periods reveal shifts in port rankings and network efficiency, highlighting the resilience of major hubs like Singapore while exposing vulnerabilities in smaller ports. The chapter concludes with actionable policy recommendations, including climate-adaptive infrastructure, digitalisation and regional collaboration, to enhance the resilience of ASEAN’s maritime transport and supply chain networks in the face of global uncertainties. The findings contribute to the discourse on sustainable maritime systems and inform strategies for fostering resilience in similar regions globally.