In today’s increasingly digitized environment, organizations face mounting pressure to secure their Information Infrastructure Systems (IIS) against complex and evolving cyber threats. While vulnerability analysis is widely practiced, it often remains confined to technical or operational layers, offering limited value for strategic decision-making. This study introduces Strategic Vulnerability Analysis as a management-oriented approach to evaluating the resilience of operational IIS, emphasizing its relevance for enterprise-wide governance. A comparative assessment of three prominent cybersecurity frameworks IT-Grundschutz, ISO/IEC 27001, and the NIST Cybersecurity Framework (CSF) is conducted to evaluate their effectiveness in supporting strategic-level risk identification, alignment, and governance. The analysis applies structured criteria to examine each framework’s strategic orientation, implementation complexity, level of abstraction, and adaptability across organizational contexts. The objective is to determine how these frameworks can best support executive decision-making and integration of cybersecurity into enterprise strategy. Building on these insights, the paper proposes a hybrid cybersecurity model that synthesizes ISO/IEC 27001’s governance structure, NIST CSF’s flexibility, and IT-Grundschutz’s technical specificity. This integrated approach aims to enhance organizational resilience and decision-making capacity. The findings provide actionable guidance for both practitioners and policymakers seeking to align cybersecurity governance with broader risk management and compliance objectives.