This chapter outlines initiatives to cultivate entrepreneurial and other related critical skills in agriscience students. The case studies and related ecosystems contributed to enhancing efforts in the faculty towards improving the entrepreneurial mindsets of both academics and students. The interventions will not only be of benefit to the students currently in the departments where this is focused on, but also, through staff/academic involvement, it will enhance the general innovation and entrepreneurship culture in the faculty and wider in the university. The links created with other faculties or parties external to our faculty are valuable, and in effect create a much-needed ecosystem when entrepreneurship initiatives are integrated into current academic offerings or alongside it.