This chapter summarizes information on personal care and consumer chemicals (PCP). In our modern lifestyle, the consumption of these chemicals has significantly increased due to their widespread use in various products, including sunscreen, shampoo, conditioner, styling products, toothpaste, mouthwash, soaps, body washes, deodorants, tampons, shaving cream, and aftershave. They can contain the following classes of substances, which are particularly important from an ecological and health perspective due to the large number of products and the nearly unmanageable number of ingredients, including bisphenols, parabens, antimicrobials, and ultraviolet filters. Additionally, they may be found in various plastic products and pharmaceutical preparations. Therefore, a brief description of the chemical and physical characteristics, usage patterns of these substances, their primary health risks, and toxicokinetic properties, as well as references to further scientific literature, are provided. The primary objective is to present the occurrence in detail in human matrices such as blood, urine, and breast milk. For this background, detailed information is provided on bisphenols, parabens, organic UV light protection filters and stabilizers, including benzophenone (BP), octocrylene, camphor derivatives, salicylates, cinnamates, benzotriazoles, and benzothiazoles, as well as synthetic musk compounds and triclosan (TCS) and triclocarban (TCC).