Lymphedema is characterized by tissue swelling and fluid retention due to inadequate lymphatic drainage, signifying dysfunction in the lymphatic system. Head and neck lymphedema (HNL) is a localized edematous condition resulting from circulatory disturbances, affecting the face and neck and internal areas such as the oral cavity, tongue, pharynx, and larynx. It occurs less frequently compared to lymphedema of the extremities. Nevertheless, when HNL progresses to a severe stage, it raises significant concerns for patients and their families. The history and physical examination are generally sufficient for diagnosing head and neck lymphedema clinically. However, when clarity is lacking or a precise assessment of therapeutic effects is required, imaging modalities become valuable. Managing lymphedema, known as complete decongestive therapy, typically involves four fundamental components. These four components comprise manual lymphatic drainage, compression therapy, exercise, and skincare. Head and neck lymphedema significantly affects individuals’ quality of life. Early diagnosis and initiation of treatment are essential for regaining functionality. The treatment approach should be tailored to each individual, according to the patient’s condition, the clinical stage of lymphedema, and underlying causes. An effective treatment plan for HNL may require a multidisciplinary approach, and physicians should collaborate closely with healthcare professionals specialized in lymphedema management. In this way, patients’ symptoms can be alleviated, lymphedema progression can be slowed down, and their quality of life can be improved.