Tricyclics are named after their three-ring molecular structure. Veterinary psychiatry makes limited use of different tricyclic antidepressants (TCAs). After describing the common characteristics of all the molecules in this family, we will detail clomipramine and amitriptyline. Other molecules, used only occasionally or anecdotally in dogs, are generally unsatisfactory and ineffective in cats. These include doxepin, which acts as a sedative in cats, and imipramine and amitriptyline, which cause hypersalivation in cats (Rodan and Heath 2016).

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Tricyclic Antidepressants

  • Stéphane Bleuer-Elsner,
  • Sylvia Masson,
  • Marie Lacoste,
  • Gérard Muller

摘要

Tricyclics are named after their three-ring molecular structure. Veterinary psychiatry makes limited use of different tricyclic antidepressants (TCAs). After describing the common characteristics of all the molecules in this family, we will detail clomipramine and amitriptyline. Other molecules, used only occasionally or anecdotally in dogs, are generally unsatisfactory and ineffective in cats. These include doxepin, which acts as a sedative in cats, and imipramine and amitriptyline, which cause hypersalivation in cats (Rodan and Heath 2016).