Regularization is essential in deformable image registration (DIR) to ensure that the estimated Deformation Vector Field (DVF) remains smooth, physically plausible, and anatomically consistent. However, fine-tuning regularization parameters in learning-based DIR frameworks is computationally expensive, often requiring multiple training iterations. To address this, we propose \(\operatorname {cIDIR}\) , a novel DIR framework based on Implicit Neural Representations (INRs) that conditions the registration process on regularization hyperparameters. Unlike conventional methods that require retraining for each regularization hyperparameter setting, \(\operatorname {cIDIR}\) is trained over a prior distribution of these hyperparameters, then optimized over the regularization hyperparameters by using the segmentations masks as an observation. Additionally, \(\operatorname {cIDIR}\) models a continuous and differentiable DVF, enabling seamless integration of advanced regularization techniques via automatic differentiation. Evaluated on the DIR-LAB [5, 6] dataset, \(\operatorname {cIDIR}\) achieves high accuracy and robustness across the dataset.

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\(\operatorname {cIDIR}\) : Conditioned Implicit Neural Representation for Regularized Deformable Image Registration

  • Sidaty El Hadramy,
  • Oumeymah Cherkaoui,
  • Philippe C. Cattin

摘要

Regularization is essential in deformable image registration (DIR) to ensure that the estimated Deformation Vector Field (DVF) remains smooth, physically plausible, and anatomically consistent. However, fine-tuning regularization parameters in learning-based DIR frameworks is computationally expensive, often requiring multiple training iterations. To address this, we propose \(\operatorname {cIDIR}\) , a novel DIR framework based on Implicit Neural Representations (INRs) that conditions the registration process on regularization hyperparameters. Unlike conventional methods that require retraining for each regularization hyperparameter setting, \(\operatorname {cIDIR}\) is trained over a prior distribution of these hyperparameters, then optimized over the regularization hyperparameters by using the segmentations masks as an observation. Additionally, \(\operatorname {cIDIR}\) models a continuous and differentiable DVF, enabling seamless integration of advanced regularization techniques via automatic differentiation. Evaluated on the DIR-LAB [5, 6] dataset, \(\operatorname {cIDIR}\) achieves high accuracy and robustness across the dataset.