This chapter explores the application of trauma- and violence-informed care (TVIC) in public health nursing practice to address the impacts of violence and trauma on individuals, families and communities. Drawing on a public health framework, it examines the intersection of structural, cultural and historical traumas with family violence, highlighting the critical role of nurses in fostering safety, resilience and equity. The chapter begins by defining TVIC and its principles, emphasising the importance of creating culturally safe care environments to prevent retraumatisation and promote trust. Next, primary, secondary and tertiary prevention strategies are described, outlining evidence-based approaches for early detection, intervention and long-term support. The chapter also addresses the overlapping and compounding effects of structural violence, cultural distress and family polyvictimisation, underscoring the need for systemic advocacy and interdisciplinary collaboration. By integrating TVIC into public health nursing, nurses can respond effectively to the multifaceted challenges of violence and trauma, contributing to improved health outcomes and social equity globally.