This chapter presents a commentary on mentoring children with incarcerated parents from the perspective of a developmental researcher. The case is made that it is particularly important to provide mentors, whether they be volunteers or professionals, who work with children with incarcerated parents with information about the growing research base on child outcomes, with training in trauma-informed approaches, and with proper support to do their work. The provision of information, training, and ongoing support has benefitted leaders and staff in programs that focus on this population. Trauma-informed approaches can build empathy and appropriate skills so that mentors can respond to children in sensitive ways, including acknowledging the possibility that some children with incarcerated parents have experienced cumulative or toxic stress. Training, knowledge, and support can help mentors provide better mentoring as well as help mentors know when referrals to additional services are needed for children and family members, which may further facilitate resilience in vulnerable children.