The chapter, through the intersecting prisms of gender and mental health, examines the ramifications of the Shakahola massacre in Kenya, an appalling event steeped in religious zealotry through religious dogma. The massacre, occurring in a remote village in Kilifi County, was driven by religious fanaticism and patriarchal constructs. Employing concepts drawn from behavioral and social theories of mental health, the chapter interrogates the incident’s context, motivations, and aftermath and illuminates power structures, religious indoctrination, and the complex interplay of gender dynamics that contributed to the tragedy. The methodology involves a multidisciplinary analysis that takes into account tertiary and secondary sources as well as media recorded information. Discussions address the entrenched patriarchy, the role of toxic masculinity, and the psychological toll of religious fanaticism. The chapter underscores the intricate interrelationship between religious extremism, gender roles, and mental health vulnerabilities and attendant potential for violence in the pursuit of dogmatic religious ideologies. Recommendations center on fostering inclusive discourse on gender, promoting mental health awareness, and challenging societal constructs that propagate harmful gender stereotypes and extremist religious ideologies. The chapter further advocates for community-based mental health interventions and education initiatives challenging religious dogma to prevent similar atrocities.