Religion is sometimes blamed for performing a conflicting and dual role in public health. On the one hand, religion plays a positive role, while on the other hand, it weakens public health interventions. The tension and ambivalence of religion in public health are widely acknowledged. This situation suggests a need to consider the root causes of this ambivalence with the view to explore ways of harnessing it for positive health outcomes. This chapter explores the following interlocked questions: why are churches ignored in public health? How could this situation be addressed to encourage effective partnerships between religious (churches) and nonreligious institutions like government ministries of health and intergovernmental organizations (IGOs) like WHO and others? What are some church-driven public health interventions that churches can implement? In addressing these questions, this chapter considers the tension and ambivalence of religion in public health and suggests an approach where ambivalence can be viewed as a positive construct that can be harnessed to develop collaborations and partnerships between churches and other public health actors. It implicitly concludes by outlining some possible public health interventions that can be implemented by churches to contribute to achieving SDGs 3, 5, and 6.