Dates are globally consumed as fresh or dried fruits, enriched with a wide range of essential nutrients that positively affect human health. Dates are economically crucial in date-harboring regions and are considered almost a wholesome diet since they are rich in carbohydrates, dietary fibers, minerals, essential vitamins, and phytochemicals. There are different varieties of dates having different chemical compositions; hence, it is important to evaluate the changes in their chemical composition during various stages of processing, such as grading, storage and packaging. Combating the microbial contamination of dates during processing without affecting their nutritional attributes is always one of the main issues in which the various nonthermal processing technologies have been employed and have received fathomable attention in recent years. Cold plasma, as a nonthermal processing technology, has emerged as one of the prominent technologies concerning the nutritional quality and microbial decontamination of agricultural produce during various stages of processing in comparison with conventional thermal processing technologies that often result in thermal damage to produce. Cold plasma is a promising technology in the food processing sector, enhancing product safety and extending shelf life. The use of cold plasma has been extended to the food industry for several years as a significant intervention in nonthermal food processing, encompassing a wide range of applications. This chapter enlightens the effect of cold plasma on the quality and various characteristics of dates. Microbial inactivation during the processing of dates by using cold plasma technology has been widely examined. The inactivation of Aspergillus niger spores, a severe threat to dates, by employing double atmospheric pressure argon cold plasma (DAPACP) is discussed in this chapter. The discussion also highlights the efficacy of cold plasma in subduing the effect of mycotoxins on dates. The change in surface properties of date fibers by cold plasma treatment, without affecting their internal properties, is also part of the discussion.