This chapter concludes the analysis throughout the book and provides a roadmap with suggestions for further application of ethics in One Health approaches. First, I make a synthesis conclusion of the book. I then turn to some practical recommendations for research, policy making and education in One Health approaches. Finally, I will draw the roadmap for ethics in One Health approaches with a summary of which frameworks that seem to be fruitful and which frameworks that can be avoided. My main finding in the book is that there is a need for a two-stage dialogue within One Health approaches and that might be the most sufficient solution. Other fruitful frameworks are the Capability Approach and the Land Ethic Decision Model.