Laser powder-bed fusion can allow for a faster and more efficient supply of aviation parts. L-PFMs must adhere to the high standards of airworthiness held by the FAA and EASA. Regulatory agencies have adopted a performance-based regulation of additive components. Components created through additive manufacturing must meet or exceed the requirements of conventionally made parts. It can be an expensive and time-intensive process, costing upwards of hundreds of thousands of dollars and several years to complete. Additive manufacturing can reduce this cost and shorten this schedule by providing game-changing solutions for standardization and qualification. When a company qualifies a component for airworthiness, they must qualify “the process” as well as “the machine” along with “the part.” The medical industry introduced a process of quality assurance referred to as installation qualification (IQ), operational qualification (OQ), and performance qualification (PQ). To explain these three efforts, please refer to the following: Some aerospace companies have begun using IQ, OQ, and PQ nomenclature, but mostly, the aerospace markets use a fixed process/first article inspection approach. The intent of this chapter is to guide the reader through the steps needed to meet the correct standards for a 3D printing process and machine.