In a time of digital disruption and rapid technological advancement, digital leadership skills, generative AI adoption, and entrepreneurial agility become essential assets for business success. This theoretical study investigates the ways in which these elements interact to affect the success of businesses run by women. Drawing on the Resource-Based View (RBV) theory, the work proposes that entrepreneurial agility fosters the adoption of generative AI, which in turn enhances women’s business performance. Furthermore, the paper posits that digital leadership capability positively moderates the relationship between generative AI usage and women’s business performance. By presenting an integrated conceptual framework, this research contributes to a deeper understanding of the dynamic capabilities necessary for women entrepreneurs to thrive in competitive, technology-driven environments.