Public transportation efficiency depends on optimized routes, schedules, and service quality. In India’s non-metropolitan cities, the Bus Rapid Transit System (BRTS) enhances connectivity through dedicated corridors. However, driver behavior significantly impacts operational safety, particularly when influenced by neuroticism-related factors like fatigue, stress, and anger. This study focuses on the Hubballi-Dharwad BRTS (HDBRTS), examining how neurotic traits affect risky driving behavior. Data from interviews with 130 HDBRTS drivers were analyzed using descriptive statistics, regression models, and Cronbach’s Alpha reliability testing. Findings revealed that neurotic characteristics—such as emotional instability, impulsivity, and stress susceptibility—reduce decision-making and reaction time, increasing accident risks. Regression analysis showed a significant correlation between neurotic traits and dangerous behaviors like signal violations and impulsive maneuvers at intersections. A Cronbach’s Alpha score of 0.686 confirmed data reliability. Key operational issues identified include frequent station skipping (42%), improper bus-door alignment (37%), and blind spot misjudgments (53%), all contributing to safety hazards. The study recommends interventions such as psychological screening during recruitment, enhanced training, and stress management programs to improve driver behavior and overall system safety. These measures are essential for ensuring the reliability and effectiveness of BRTS in rapidly growing urban environments.