Most children experience at least one traumatic event before age 16. Whether singular and acute, or multiple and chronic, the experience of trauma can have lasting effects on biopsychosociocultural functioning that can reverberate across generations. Still, it can be difficult to recognize, evaluate, and respond to a youth’s trauma. This chapter explores culturally responsive methods of assessing trauma in the context of referral questions that may not clearly point to trauma exposure. We explain how clinicians can attune to the diverse signs of trauma in the context of their assessments, including behavioral, cognitive, emotional, physical, and psychological symptoms. Then, we present multimodal methods for evaluating both trauma exposure and the effects of trauma, including through record reviews, self- and collateral-report screening instruments and more comprehensive measures, and structured and unstructured interviews. Finally, this chapter turns to a variety of diagnostic labels that summarize the constellation of symptoms that can arise following trauma events across cultures. Through case examples, we illustrate how these principles, strategies, and techniques can be adapted for clients across many ages, cultures, and developmental levels throughout assessment contexts.