Deep eutectic solvents (DES) represent an environment-friendly and adaptable substitute for conventional solvents due to their low toxicity, biodegradability, and customizable characteristics. Due to their expanding uses in inorganic synthesis, electrochemistry, pharmaceuticals, and nanotechnology, DES have emerged as the preferred option. The capacity of DES to solubilize metal ions and regulate nanoparticle development renders them exceptionally advantageous in catalysis, energy storage, and metal processing. The constraints of DES include increased viscosity, thermal instability, and scalability issues. DES are poised to transform green chemistry and sustainable industrial processes, leading to a more sustainable future. This chapter outlines the properties and various applications of DES for the synthesis of inorganic nanoparticles, including metals, metal oxide nanoparticles, etc.