The use of Digital Technologies (DTs) combined with Circular Economy (CE) practices is becoming increasingly promising. However, there is still a gap between industry and academia in terms of education and the professionalization of individuals within this domain. Given this context, this study presents the structure of a cross-disciplinary course developed under an EU-funded project that aims to empower humans in terms of knowledge and competencies for digital and circular transition. The course encompasses four sessions: 1. Digital Technologies and Circular Economy; 2. Virtual and Augmented Reality for Circular Economy; 3. The Role of Automation in Circular Economy; and 4. Data Analysis for Circular Manufacturing. Throughout the sessions, content on digital technologies applied to developing more sustainable solutions is explored. Each session supports the development of essential skills such as automation and data management, as well as an understanding of DTs applications, which play a critical role in the current era of systemic changes, including climate change, digitalization, and business adaptation.