Neural therapy has come a long way since the end of the twentieth century, becoming a complex medical system called Neuraltherapeutic Medicine. It was first introduced to the country by doctors Germán Duque and Julio Cesar Payán de la Roche, who started its epistemological qualification and clinical practice with critical thinking in the south of the country. Dr. Payán also led a training process for health professionals, which he later linked to the university academy. The “La Nueva Esperanza” Health Center is a key setting for this, and its experience is described in this chapter. Neuraltherapeutic medicine, following a biocentric approach, proposes an integral individual, collective, and environmental health management aimed at promoting health and well-being and preventing disease. It follows the principles of self-eco-organization for the care of life as a fundamental right, not mechanistic or positivist, which questions the classic approaches of clinical biomedical therapy and classic public health policies. The practical experience of collective and community health management in Popayán, Colombia, exemplifies the social component. Here, it interacted for several years with the primary care of the public health system, under elements of social medicine and community health, using community participation, such as Participatory Action Research. This process was characterized by the women’s participation in the management of the social determination of health, their social and environmental determinants with humanistic principles, less drug dependent, and more decisive and cost-effective.