Local anesthetics are molecules that reversibly inhibit electrical conduction within the membranes of excitable cells by blocking sodium channels. This action prevents nerve conduction and the transmission of painful sensations, making them extensively utilized in the management of both acute and chronic pain. Additionally, local anesthetics possess anti-inflammatory, neuromodulatory, and antiarrhythmic properties due to their interactions with G protein receptors, NMDA receptors, and other ion channels. In the context of Neuraltherapeutic medicine, the goal is to facilitate the body’s self-organization by providing appropriate stimuli tailored to the patient’s individual life history.