In the past, the autonomic nervous system and the immune system were assigned different functions. However, it has become increasingly clear that these systems are inseparable and that they communicate closely with each other—hence the name “neuroimmune system.” Within this communication, we found interdependent positive feedback loops (iterations). Iterative, holistic systems have the fundamental ability to reorganize themselves after a stimulus or a nonspecific “reset” by local anesthetics (neural therapy). I hope I understood right and shortened the abstract.