For many years, the Republic of South Africa has been one of the economic powers on the African continent and has always played a major role in relations with its neighboring countries. It is therefore natural that cross-border exchanges would take place on all levels of cuisine development. This chapter offers an introductory insight into the environmental and agricultural business of South Africa within the larger Southern African and African continent context. An introductory summary of the cuisine of the four demographic groups of South Africa is discussed, with reference to similarities found in countries sharing South Africa’s borders. The chapter ends with the ruinous obesity and overweight circumstances in the region, possibly as a result of increased dietary changes that come with aspirational lifestyles and living conditions that modern Southern African people have to compete with.