Billions of people, almost 40% of the world’s population, are either overweight or underweight, which is a direct consequence of the food environment. In more and more countries in the world, people are overweight in a large part due to the obesogenic food environment. The obesogenic environment leads to overconsumption of energy; it is obvious that sensory characteristics of food have a tremendous impact on food choice and food intake. This chapter deals with the effects of texture, taste, and smell on intake. The effects of texture on energy intake is dramatic. Liquid and soft foods are consumed at much higher eating rates compared to more harder foods. The energy intake rate of energy dense liquids (sugar sweetened beverage) and soft solids (like cake, sausage roll, meatball) is in the range of 150–450 kcal/min, quickly leading to overconsumption of energy. Liquid and soft solid calories are not well sensed by the sense of taste, due to their short oro-sensory exposure time per kcal ingested. Various recent studies show that across the food supplies in Australia, Malaysia, the Netherlands, and the USA, sweetness, umami, saltiness, and fat sensation intensities relate to concentrations of carbohydrates, protein, salt, and fat in food. So, taste serves as a nutrient sensing system, and this sensing system contributes to satiation. The role of smell is different. Retronasal smell sensations coming through flavors within foods does not have an impact on satiation; odors in the environment may lead to sensory-specific appetites. In summary, sensory signals from food have a large impact on energy intake, and designing foods in an optimal way may help to develop foods with a higher satiating efficiency, while maintaining palatability. In this way we can make the healthy choice the happy choice.