This introductory chapter sets the stage for an exploration of the evolving landscape of healthcare in Asia, a region marked by immense diversity and dynamic change. It addresses the complexities inherent in defining “Asia”, highlighting the heterogeneity that shapes healthcare needs and opportunities across the continent. As part of the “Futures of Asia” series, this chapter outlines the book’s interdisciplinary approach, drawing upon conceptual frameworks, reviews, and empirical studies to examine the forces shaping the future of healthcare in this region. It introduces the book’s structure, arranged into sections focusing on building healthy societies, advancing health and care, and leveraging health technology, including artificial intelligence. Furthermore, this chapter emphasises the cross-cutting themes of equity, innovation, and technology, particularly in the context of pandemic preparedness and the integration of artificial intelligence and telemedicine. By providing a roadmap of the diverse perspectives and methodologies employed, this introduction invites readers to delve into the pathways that will determine what the future holds for healthcare in Asia, ultimately aiming to stimulate critical dialogue and contribute to the development of more equitable, accessible, and effective healthcare systems.