The integration of Artificial Intelligence (AI) into medical imaging modalities has ushered in a new era of diagnostic precision and efficiency. This chapter delves into AI’s transformative role in enhancing the quality and capabilities of imaging technologies such as MRI, CT, and ultrasound. Explores AI-driven advances in noise reduction, artifact removal, and super-resolution imaging, which significantly improve diagnostic accuracy and clinical outcomes. Moreover, the chapter examines AI’s contributions to real-time guidance during image acquisition, optimized imaging systems, and low-dose imaging techniques. The discussion extends to innovative AI applications in image reconstruction, leveraging faster algorithms and advanced techniques such as compressed sensing to produce high-quality 3D and 4D images. By enabling disease detection, pattern recognition, and quantitative imaging, AI increases radiologists’ capabilities through robust decision support systems. Highlighting applications across various imaging modalities, the chapter envisions future trends in AI-enhanced imaging, including ultra-low-dose imaging, real-time imaging, and compact AI-powered devices. Following an in-depth analysis, this chapter highlights the importance of AI in driving these developing imaging modalities toward better patient care and precision medicine.