E-commerce platforms often overlook the needs of users with color vision impairments and low literacy, creating accessibility challenges. Traditional designs rely on visual cues and text, making navigation difficult. This study proposes a system that improves accessibility through dynamic color inversion, voice-command navigation, face recognition payment, regional language translation, and interactive text-to-speech. By integrating these features, the system aims to set new accessibility standards, enabling users with color vision deficiencies and low literacy to engage with e-commerce platforms, fostering a more inclusive and seamless online experience.