In this essay, I propose to interrogate the opportunities for, and historical obstacles to, a Black-Native American political alliance in the United States, as these groups confront an ongoing program of colonial violence marshaled against them. It is my argument that these opportunities and obstacles exist as artifacts of a difficult and complex history tragically punctuated by both Native and Black cooperation with a White Nationalist, settler-colonial, program in North America. Furthermore, I argue that, given the contemporary reality of unrelenting state violence against Black and Native American communities, a unified struggle is an obvious choice for activists, organizers, and community stakeholders.