Nursing homes accommodate increasing numbers of people with dementia, with increasingly severe stages of dementia. With the growing pressure on care, a multi-sensory room may be a solution, by improving the social and emotional wellbeing of people with dementia. In this qualitative study, the perspectives of family and formal caregivers on the use and adoption of a multi-sensory room was researched. The goal was to improve the implementation and use of the room in a Dutch nursing home. Focus groups revealed three main psychological themes that influence the use of the room by family members, namely: the level of knowledge about the room, how competent one feels to use it independently and the need to connect with the person with dementia. Semi-structured interviews with caregivers showed four psychological factors that play a role in the effective use of the multi-sensory room: feelings of overpower, uncertainty and lack of knowledge about the room, enthusiasm and social influence of colleagues. Recommendations include: clear, non-written instructions; social meetings for family; a training to effectively communicate purpose and benefits of this innovation, and emphasizing the communication and relational connection that can be strengthened between people with dementia and family members through the multi-sensory room.