Scholarlink

Partially specified Boolean networks (PSBNs) provide a formal framework for the qualitative modelling of gene regulatory networks or signalling pathways in which the logic of interactions is not completely known. The tool AEON has been well-established in handling attractor analysis of PSBNs efficiently. The PSBN framework has been recently extended with algorithms supporting phenotype control allowing to stabilise the network in states exhibiting given traits. In this paper, we present a novel version of the AEON tool that supports phenotype control.

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

AEON 2025: Robust Control of Partially-Specified Boolean Networks

  • 会议论文

  • 发表日期：

    2026年

查看全文
  • Vojtěch Veselý,
  • Eva Šmijáková,
  • Samuel Pastva,
  • Nikola Beneš,
  • David Šafránek

摘要

Partially specified Boolean networks (PSBNs) provide a formal framework for the qualitative modelling of gene regulatory networks or signalling pathways in which the logic of interactions is not completely known. The tool AEON has been well-established in handling attractor analysis of PSBNs efficiently. The PSBN framework has been recently extended with algorithms supporting phenotype control allowing to stabilise the network in states exhibiting given traits. In this paper, we present a novel version of the AEON tool that supports phenotype control.