In this chapter, we propose an innovative research approach to unearth the factors and determinants, which are often hard to attain with the conventional research methods, that significantly contribute to the social exclusion and marginalization of persons with disabilities. Our proposed Inside-Out research approach builds on the strengths of established qualitative research—referenced as a research case in the chapter—and the unique opportunities of personal stories of children with disabilities and their families referenced as lived experience cases. In this chapter, we offer a distinctive contribution to the global disability and inclusion research community by balancing the theoretical rigor rooted in the global North with the community-based practice located in the global South represented by the case of Uzbekistan. We shed light on typically unnoticed power structures and their enforcement mechanisms by zooming into the cultural and institutional value systems that equip the disability and inclusion researchers with insightful qualitative data. The intersection of Critical Disability Theory (CDT) (Devlin & Pothier, Critical disability theory: Essays in philosophy, politics, policy, and law. UBC Press, 2006) and DisCrit (Annamma et al., Dis/ability critical race studies (DisCrit): Theorizing at the intersections of race and dis/ability. Race Ethnicity and Education, 16(1), 1–31, 2013)—major theoretical frameworks with the Critical Discourse Analysis (CDA) (Fairclough, Critical discourse analysis: The critical study of language. Longman, 1995)—the analytical framework—helped us to emphasize the rationality and urgency of interdisciplinary approach to researching disability and inclusion in the global South context.