The concept of “Artificial Intelligence,” first coined by John McCarthy in 1956, has undergone substantial evolution, from early computational models such as Logic Theorist to the sophisticated deep neural networks advanced by Hinton and collaborators. Fortified by exponential increases in computational capacity, AI has emerged as a critical tool across numerous scientific fields. Among these diverse areas, the health system has gained significant promise for practical application. Considering the effects of deep learning and generative AI, we are now in the “AI Transformation of Medicine” era.