This chapter outlines the methodology developed within the European LIFESeedNEB project, which seeks to integrate the principles of the New European Bauhaus and Nature-Based Solutions to transform urban environments in Lorquí (Spain), Potenza (Italy), and Dunaújváros (Hungary). The project addresses local challenges by promoting biodiversity, enhancing climate resilience, and improving citizen well-being through actions such as the restoration of green spaces, pollution reduction, and climate risk mitigation. A participatory governance approach is adopted, ensuring active citizen engagement and fostering public–private collaboration to deliver inclusive, context-specific interventions aligned with the Sustainable Development Goals and the European Urban Agenda. The methodology for identifying actions is based on local climate resilience challenges and follows the recommendations of the EKLIPSE Expert Working Group, incorporating indicators from the EU report Evaluating the Impact of Nature-based Solutions: A Handbook for Practitioners. This evidence-based framework ensures the relevance and effectiveness of the proposed interventions while supporting the integration of sustainability principles into local policies. Finally, the chapter examines how the methodology was adapted to the specific urban contexts of the three case studies, ensuring that the implemented solutions have a tangible impact on quality of life and contribute to the sustainable transformation of these European cities.