DNA analysis of certain Scottish families has revealed their Mesopotamian origins as well as their migration routes to Scotland via Scandinavia and Normandy. Some of the families arrived in England from Normandy with William the Conqueror via the English Channel following the Norman conquest of England in 1066, some of whom later settled in Scotland at the time of King David I. However, the history of the Vikings arriving in Scotland goes back to around the end of the eighth century CE when they used to take various sea routes including direct routes from Scandinavia to the Scottish Northern Isles, the Shetlands and Orkneys, in addition to other sea routes which were longer and less used. The families who settled in Scotland contributed significantly to the social and economic development leading to the creation of a unique Scottish culture. While previous studies have focused on the genetic makeup of the Vikings showing population differences, the DNA analysis discussed in this paper suggests that many of the Vikings were European settlers mainly from the Scandinavian countries. However, some of the Viking leaders were in fact immigrants with ancestral origins in the ancient historical region of Mesopotamia. The DNA analysis suggests that members of ancient Mesopotamian dynasties arrived in Scandinavia via Anatolia and across Europe and controlled the regional populations as Viking leaders and ruling dynasties including Danish monarchs as well as the Norman kings of England and their relatives.