It has been found that the symptomatic burden of HSDD is negatively and statistically significantly associated with patients’ mental health; the impact was greater among premenopausal women compared to those in postmenopause. However, although HSDD affects the quality of life and interpersonal relationships of the patient, the disorder often goes unaddressed or untreated. Recent studies on the disease burden in women with HSDD, particularly in premenopausal women, are limited.