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One limitation of response assessment in glioma using conventional MRI is its reliance on the measurement of contrast enhancement reflecting a disrupted blood–brain barrier. This signal may be normalized by antiangiogenic therapy, known as pseudoresponse. Amino acid PET tracers offer a more sensitive method to identify viable glioma tissue.

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Case 38: Pseudoresponse in Glioblastoma

  • 章节

  • 发表日期：

    2025年

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  • Ian Law,
  • Jonathan F. Carlsen,
  • Benedikte Hasselbalch

摘要

One limitation of response assessment in glioma using conventional MRI is its reliance on the measurement of contrast enhancement reflecting a disrupted blood–brain barrier. This signal may be normalized by antiangiogenic therapy, known as pseudoresponse. Amino acid PET tracers offer a more sensitive method to identify viable glioma tissue.