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Hypothalamic hamartomas are lesions associated with chronic seizures and an epileptic encephalopathy of heterogeneous severity. We describe a case of [18F]FDG PET brain imaging in a patient with a left sided hypothalamic hamartoma showing extensive left hemispheric cortical metabolic abnormalities. A careful multidisciplinary analysis of clinical, electrophysiological, and imaging data allowed to exclude the presence of a concomitant cortical lesion in the hypometabolic areas. The patient underwent radio-surgery, with a favorable outcome.

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Case 28: Hypothalamic Hamartoma with Cortical Metabolic Abnormalities

  • 章节

  • 发表日期：

    2025年

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  • Valentina Garibotto,
  • Maria Isabel Vargas,
  • Serge Vulliemoz,
  • Margitta Seeck

摘要

Hypothalamic hamartomas are lesions associated with chronic seizures and an epileptic encephalopathy of heterogeneous severity. We describe a case of [18F]FDG PET brain imaging in a patient with a left sided hypothalamic hamartoma showing extensive left hemispheric cortical metabolic abnormalities. A careful multidisciplinary analysis of clinical, electrophysiological, and imaging data allowed to exclude the presence of a concomitant cortical lesion in the hypometabolic areas. The patient underwent radio-surgery, with a favorable outcome.