Conductive polymers (CPs) are organic materials known for their distinct optical and electrical properties resembling metals and inorganic semiconductors. CPs such as polyaniline (PANI), polypyrrole(PPy), polythiophene(PTh), and derivatives like aniline oligomer and poly(3,4-ethylenedioxythiophene) (PEDOT) can be synthesized using simple, adaptable, and cost-efficient approaches. These materials can be established into multifunctional supramolecular structures via basic electropolymerization techniques. Various methods have been developed to modify and optimize CPs, making them suitable for integration into biomedical applications, including biomaterials and biosensors. Advances in CP technology are particularly significant in bioengineering, regenerative medicine, and biosensing, offering the potential for future innovation. CPs have demonstrated the ability to activate different cellular mechanisms, broadening their applicability in the biomedical sector. This review includes information on desired CP qualities pertinent to biomedical applications and specifics on how CPs have been modified to create these traits.