The University of Modena and Reggio Emilia (Unimore), a member of the Italian Universities Network for Sustainable Development, has developed a comprehensive, integrative approach to sustainability across education, research, and community engagement. This paper examines Unimore’s sustainability initiatives, including its contributions to the Emilia Romagna Region’s Pact for Work and Climate, its participation in international networks such as Hydrogen Europe Research, and its local community outreach through projects like the Zero Carbon City initiative. Unimore’s interdisciplinary Sustainability course, launched in 2021, and its research in fields like hydrogen technology, demonstrate the university’s commitment to fostering sustainable practices. The paper concludes with a discussion of Unimore’s prospects, potential limitations, and the broader implications of its initiatives for sustainable development in higher education.