Although African countries contribute less to global greenhouse gas (GHG) emissions than the majority of other nations, the effects of climate change have designated the continent as one of the most vulnerable to the impacts of climate change. The effects of climate change have continued to threaten the public safety of the environment and its resources, which humans and animals depend upon for survival. In Nigeria, environmental resource scarcity caused by climate change has shaped the relationship between humans and cows over the past decades. The increasing desertification, extreme weather occurrences, and gradual disappearance of wetlands, especially in the country’s northern region, traditionally home to large herds of cow rearing, have dislodged herders from their mode of subsistence without any sustainable alternative livelihood plans. The exigencies of this situation have driven many herders into restiveness and sundry patterns of unusual survival practice, leading to violent confrontations between humans and cows, the politicisation of cow-human relations, and environmental contestation. Using a qualitative methodology that relies on secondary data, this chapter aims to reflect discursively on the mitigation stage of Nigeria’s cow-human climate change-induced relationship and set the premise for more rigorous causal analysis to establish the linkage between climate change, humans, and animals.