This chapter explores the psychosocial factors that promote resilience in adolescents exposed to adverse contexts. Resilience, understood as the capacity to overcome and learn from adverse experiences, is not a static characteristic but a dynamic process shaped by individual, family, social, and cultural factors. Specifically, the chapter addresses three central correlates: well-being, social support and integration, and mental health. The well-being of resilient adolescents is manifested in high levels of life satisfaction, positive emotions, and stressStress management skills. This well-being includes psychological, physical, and social dimensions and is essential for coping with the challenges of adolescence. For their part, emotional and practical support from friends, family, and significant others strengthens adolescents’ ability to cope with difficulties. Strong social networks foster constructive coping strategies and act as buffers against stressful situations. In terms of mental health, resilience is linked to lower levels of anxiety, depression, and post-traumatic stress, as well as better psychological functioning. Adaptive coping strategies, such as positive thinking and active problem-solving, are key in this process. The chapter also emphasizes the need to overcome approaches focusing solely on individual and adult-centric factors. It proposes considering the collective dimensions of resilience and recognizing the cultural and socioeconomic diversity of adolescents in Latin America, especially in contexts of vulnerability. Lastly, this analysis invites reconsideration of the design of public policies and intervention strategies that strengthen adolescents’ resilient capacities and promote their overall well-being in adverse environments.