Sustainable urban planning involving vegetation coverVegetation cover is a transformative approach for creating cleaner and healthier cities. Incorporating green spaces into urban landscapes helps balance environmental, social, and economic well-being. Urban air, water, and soil get polluted from sources like automobile and industrial discharges, as well as municipal waste dumping. Control of such pollution is a critical issue that requires prioritized attention, as it poses serious risks to human health. Botanical solutions such as phytoremediationPhytoremediation have tremendous importance in recent times in the sustainable management of pollutants, where plants are utilized to remove contaminants, including heavy metals, from soil and water. Similarly, air pollution-tolerant plants can be used to clean volatile toxic compounds released from automobiles and industries into the atmosphere of urban areas. This chapter has been prepared as a comprehensive and precise document by pulling together published information on some potential pollution-tolerant plants to create vegetation coverVegetation cover and their pollution mitigation mechanisms to help in the sustainable planning of urban infrastructures like bioswales as a pollution management strategy. The possibility of prospecting the naturally occurring native wasteland plants as potential and resilient candidates for sustainable remediation of urban pollutants by the process of phytoremediationPhytoremediation is especially emphasized here. Scientific suggestions on potential plants included in this chapter will aid in developing sustainable urban planning for a better and healthier future. Researchers, environmentalists, urban planners, as well as policymakers, will benefit from the information cited in this chapter.