This research explores the role of Occupational Therapists in the hospital context, utilizing the integration of Service Design and Design Management, both of which offer benefits in problem-solving and service optimization. The objective was to investigate the practice of Occupational Therapists in the hospital environment, considering the interaction between Service Design and Design Management. The research was conducted through a Case Study involving three Occupational Therapists from a public hospital in the state of Santa Catarina, Brazil, and an Integrative Literature Review, which included nine selected studies. It was structured with the support of the Design Management tool, the Project Development Guidance Guide (GODP), and Service Design tools, encompassing data collection, analysis, and organization regarding the practice of three Occupational Therapists in a public hospital in Santa Catarina. This process resulted in the development of the Therapists’ Profile, Routine Map, mapping of Involved People, and Stakeholder Map, facilitating a deeper understanding of the Therapists’ roles, profiles, and interactions. The integration of Design Management and Service Design proved to enhance the work of these Therapists in the hospital environment, aiding in the comprehension of hospital structures and occupational Therapy activities, while broadening the understanding of their professional practices.