This chapter discusses the regulation of microvascular resistance and responses in the coronary circulation. This chapter is divided into seven sections: Introduction and Background, Metabolic Regulation of Coronary Microvascular Resistance, Endothelial and Myogenic Mechanisms, Neurohumoral Control, Cardiac Lymphatic Microcirculation, Pathophysiological Disturbances, and Summary and Future Directions. Each section contains a recent view about the key factors and mechanisms that underscore the control of the coronary microvascular resistance.

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Regulation of Coronary Microvascular Resistance in Health and Disease

  • Song Yi Shin,
  • Adam G. Goodwill,
  • Vahagn Ohanyan,
  • Liya Yin,
  • Feng Dong,
  • Ping Zhang,
  • Leah Choban,
  • Catherine Nicole Domingo,
  • Sarah Godel,
  • Emily Kodash,
  • Anna Martin,
  • Taylor Yamamoto,
  • Christian Bittner,
  • William Chilian

摘要

This chapter discusses the regulation of microvascular resistance and responses in the coronary circulation. This chapter is divided into seven sections: Introduction and Background, Metabolic Regulation of Coronary Microvascular Resistance, Endothelial and Myogenic Mechanisms, Neurohumoral Control, Cardiac Lymphatic Microcirculation, Pathophysiological Disturbances, and Summary and Future Directions. Each section contains a recent view about the key factors and mechanisms that underscore the control of the coronary microvascular resistance.