This chapter explores the impact of climate change on alpine medicinal plants, focusing on how these plants have evolved physiological and morphological adaptations to survive in harsh and changing environments. Alpine regions, known for their extreme weather conditions, are home to a variety of plants that have developed unique mechanisms to cope with cold temperatures, high radiation, and fluctuating weather patterns. As global temperatures rise, these plants face new challenges, including shifts in precipitation patterns, warmer winters, and altered growing seasons. This chapter examines the specific adaptive traits, such as changes in metabolism, growth patterns, morphology, and reproductive strategies, that enable these plants to thrive despite environmental stressors. By understanding these adaptations, the chapter highlights the potential for alpine medicinal plants to maintain their properties and show resilience or sensitivity in terms of growth and survival, even as their habitats are altered, offering valuable insights for their conservation and sustainable use in the face of climate change.