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Advanced adenomas are adenomas at a high risk of developing into cancer. They are defined by size and by histology. The definitions have been extrapolated from the Atkin study published by the group from St. Mark’s Hospital in 1992, which looked at metachronous symptomatic cancers presenting after removal of index adenomas during rigid proctoscopy [1]. This question discusses the suitability of the original criteria for defining advanced adenomas 33 years after their publication.

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How Do You Define Advanced Colorectal Adenomas, Where Did the Definition Come from, and Is It Applicable to Contemporary Practice?

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  • 发表日期：

    2025年

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  • James M. Church

摘要

Advanced adenomas are adenomas at a high risk of developing into cancer. They are defined by size and by histology. The definitions have been extrapolated from the Atkin study published by the group from St. Mark’s Hospital in 1992, which looked at metachronous symptomatic cancers presenting after removal of index adenomas during rigid proctoscopy [1]. This question discusses the suitability of the original criteria for defining advanced adenomas 33 years after their publication.